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Jan-Feb 2020;38 Suppl123(1):99-104

188 CTE can also lead to atypical astrocyte responses that contribute to recurrent seizures

The study also reported changes in the signaling-related proteins c-Fos, c-Jun, and Egr-1

Interestingly, we found that SARA-CoV-2 derived EC damage creates oxygen-deprived conditions in the lungs that not only induce metabolic reprogramming of various immune cell subsets, but also themselves

Table 3: Dose Reduction for Pemetrexed (single-agent or in combination) and Cisplatin Neurotoxicity Discontinuation Recommendation: Pemetrexed therapy should be discontinued if a patient experiences any hematologic or nonhematologic Grade 3 or 4 toxicity after 2 dose reductions or immediately if grade 3 or 4 neurotoxicity is observed